Elizabeth E Gardiner Selected Research

platelet membrane glycoprotein VI

11/2015	The platelet Fc receptor, FcγRIIa.
1/2014	Targeting GPVI as a novel antithrombotic strategy.
3/2009	Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding.
12/2007	Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI.
6/2007	A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway.
12/2004	Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase.

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Elizabeth E Gardiner Research Topics

Disease

42	Thrombosis (Thrombus) 02/2022 - 01/2002
9	Thrombocytopenia (Thrombopenia) 05/2022 - 01/2008
7	Hemorrhage 11/2022 - 01/2014
6	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2020 - 05/2009
4	Sepsis (Septicemia) 01/2022 - 01/2018
3	Inflammation (Inflammations) 05/2022 - 01/2018
3	Infections 01/2022 - 11/2012
3	Stroke (Strokes) 02/2011 - 10/2005
2	Rupture 01/2022 - 02/2011
2	Atherosclerotic Plaque (Atheroma) 01/2020 - 02/2011
2	Myocardial Infarction 08/2010 - 10/2005
1	Anemia 11/2022
1	Amyloidosis 11/2022
1	Cryoglobulinemia 11/2022
1	Lymphoma (Lymphomas) 11/2022
1	Hemolytic-Uremic Syndrome 05/2022
1	Thrombotic Microangiopathies 05/2022
1	Thrombotic Thrombocytopenic Purpura 05/2022
1	Gas Gangrene (Gangrene, Gas) 01/2022
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2022
1	Obesity 01/2021
1	Wounds and Injuries (Trauma) 01/2020
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2020
1	Critical Illness (Critically Ill) 01/2020
1	Acute Promyelocytic Leukemia 10/2019
1	Pathologic Constriction (Stenosis) 06/2019
1	Plague (Bubonic Plague) 02/2018
1	Thromboembolism 05/2017
1	Rheumatoid Arthritis 01/2017
1	Pulmonary Embolism 09/2016
1	Bernard-Soulier Syndrome (Giant Platelet Syndrome) 12/2015

Drug/Important Bio-Agent (IBA)

17	CollagenIBA 01/2020 - 06/2003
16	Glycoproteins (Glycoprotein)IBA 07/2021 - 06/2003
9	von Willebrand FactorIBA 11/2022 - 01/2002
7	Biomarkers (Surrogate Marker)IBA 05/2022 - 05/2009
6	Hemostatics (Antihemorrhagics)IBA 05/2022 - 08/2011
6	platelet membrane glycoprotein VIIBA 11/2015 - 12/2004
5	Collagen ReceptorsIBA 02/2022 - 06/2007
5	Thrombin FDA Link 01/2020 - 01/2014
4	Heparin (Liquaemin)FDA LinkGeneric 01/2020 - 01/2008
3	Proteins (Proteins, Gene)FDA Link 05/2022 - 01/2021
3	AntibodiesIBA 01/2022 - 01/2010
3	collagen-related peptideIBA 01/2020 - 12/2004
3	adhesion receptorIBA 09/2016 - 06/2003
3	LigandsIBA 11/2015 - 04/2010
3	Metalloproteases (Metalloproteinases)IBA 05/2012 - 12/2007
3	Platelet Membrane GlycoproteinsIBA 01/2012 - 01/2002
2	Platelet Factor 4IBA 01/2022 - 11/2015
2	InflammasomesIBA 01/2022 - 01/2018
2	Blood Coagulation Factors (Coagulation Factor)IBA 01/2022 - 01/2014
2	Fibrinogen (Factor I)FDA Link 07/2021 - 01/2018
2	Inosine Triphosphate (ITP)IBA 01/2020 - 10/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 02/2015
2	EnzymesIBA 01/2018 - 02/2011
2	ImmunosorbentsIBA 01/2018 - 02/2011
2	Snake Venoms (Snake Venom)IBA 04/2010 - 12/2007
1	Immunoglobulin M (IgM)IBA 11/2022
1	AnticoagulantsIBA 11/2022
1	Agammaglobulinaemia Tyrosine KinaseIBA 11/2022
1	ParaproteinsIBA 11/2022
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 11/2022
1	thiamine triphosphorate (TTP)IBA 05/2022
1	Complement System Proteins (Complement)IBA 05/2022
1	CalciumIBA 01/2022
1	VaccinesIBA 01/2022
1	IonsIBA 01/2022
1	Interleukin-18 (Interleukin 18)IBA 01/2022
1	ChAdOx1 nCoV-19IBA 01/2022
1	IgG Receptors (Fc gamma RI)IBA 01/2022
1	Protein Tyrosine PhosphatasesIBA 01/2022
1	CytokinesIBA 01/2022
1	PhosphopeptidesIBA 01/2021
1	glenzocimabIBA 01/2020
1	FibrinIBA 01/2020
1	Immunoglobulin Fab FragmentsIBA 01/2020
1	Type C PhospholipasesIBA 01/2020
1	PlacebosIBA 01/2020
1	Tyrosine (L-Tyrosine)FDA Link 01/2020
1	src-Family KinasesIBA 01/2020
1	Fibrillar CollagensIBA 01/2020
1	Protein Kinases (Protein Kinase)IBA 10/2019
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 10/2019
1	Collagen Type I (Type I Collagen)IBA 06/2019
1	Matrix Metalloproteinase 13IBA 07/2018
1	Unilamellar LiposomesIBA 01/2018
1	Peptides (Polypeptides)IBA 01/2018
1	protease-activated receptor 4IBA 01/2018
1	IntegrinsIBA 01/2018
1	Thalidomide (Thalomid)FDA Link 05/2017
1	PhosphatidylserinesIBA 09/2016
1	DNA (Deoxyribonucleic Acid)IBA 01/2016
1	AntigensIBA 01/2016
1	Peptide Hydrolases (Proteases)FDA Link 01/2016
1	P-SelectinIBA 01/2016

Therapy/Procedure

9	Therapeutics 11/2022 - 01/2014
1	Immunotherapy 11/2022
1	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2020
1	Platelet Transfusion (Blood Platelet Transfusions) 01/2020
1	Lasers (Laser) 01/2018
1	Heart-Assist Devices 01/2016